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Lyudmila I Rachek Selected Research

DNA Repair Enzymes

1/2016Mitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and Metastasis.
8/2013Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1.
1/2012Protection from palmitate-induced mitochondrial DNA damage prevents from mitochondrial oxidative stress, mitochondrial dysfunction, apoptosis, and impaired insulin signaling in rat L6 skeletal muscle cells.
4/2006Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria.

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Lyudmila I Rachek Research Topics

Disease

7Insulin Resistance
01/2019 - 11/2009
7Mitochondrial Diseases (Mitochondrial Disease)
08/2013 - 01/2004
3Type 2 Diabetes Mellitus (MODY)
01/2019 - 04/2006
2Breast Neoplasms (Breast Cancer)
06/2021 - 01/2016
2Neoplasm Metastasis (Metastasis)
06/2021 - 01/2016
1Inflammation (Inflammations)
01/2019
1Carcinogenesis
01/2016
1Neoplasms (Cancer)
01/2016
1Obesity
01/2013
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2007

Drug/Important Bio-Agent (IBA)

10Mitochondrial DNA (mtDNA)IBA
06/2021 - 01/2004
4DNA Repair EnzymesIBA
01/2016 - 04/2006
4Nonesterified Fatty Acids (NEFA)IBA
01/2014 - 04/2006
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2016 - 07/2007
3PalmitatesIBA
08/2013 - 01/2012
28-hydroxyguanineIBA
01/2016 - 08/2013
2DNA Glycosylases (DNA Glycosylase)IBA
01/2016 - 08/2013
2LipidsIBA
01/2014 - 01/2013
2Insulin (Novolin)FDA Link
08/2013 - 01/2012
1Biomarkers (Surrogate Marker)IBA
01/2019
1Adenosine Triphosphate (ATP)IBA
08/2013
1LyasesIBA
08/2013
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2013
1Glucose (Dextrose)FDA LinkGeneric
01/2012
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
11/2009
1LigandsIBA
11/2009
1ThiazolidinedionesIBA
11/2009
1Rosiglitazone (Avandia)FDA Link
11/2009
1PPAR gammaIBA
11/2009
1Troglitazone (Rezulin)FDA Link
11/2009
1Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2006
1PyrimidinesIBA
01/2004